3 Medical Instruments Stocks With Potential to Outperform

In recent years, the medical instrument industry, part of the wider Medical sector, has seen a transformation in the nature of its business, leading to higher research and development activities for developing cutting-edge technologies. The industry’s landscape changed further with the onset of the COVID-19 crisis that put robotic and remote services in the limelight. Although the majority of economies have opened up following strict lockdowns in the past couple of years, the demand for robotic and remote services is likely to remain.

However, the industry is currently facing several challenges, including supply-chain challenges, a shortage of semiconductor chips and global inflationary pressure. These developments have resulted in an extremely tough situation related to raw material and labor costs as well as freight charges. The shortage of semiconductor chips has resulted in a delay in the production of commercialized products.

Although the industry faced headwinds, a few medical instrument companies were able to maintain their recovery trend in the first nine months of 2022. Moreover, the ongoing macro headwinds are likely to improve in 2023, which should help top-line and bottom-line growth.

Here we discuss three medical instruments stocks — ShockWave Medical SWAV, iRadimed IRMD and Tactile Systems Technology TCMD — which are likely to outperform the industry going forward amid an improving world economy and easing macro headwinds. These stocks carry a Zacks Rank #2 (Buy) each. These stocks also have a Momentum Score of A or B, which indicates that these would be good stocks for momentum investors based on recent price changes and earnings estimate revisions. Meanwhile, the underperformance of iRadimed and Tactile Systems in the past six months compared with the Zacks Medical – Instruments industry may lead to a rally in these stocks on the back of strong fundamentals. You can see the complete list of today’s Zacks #1 Rank (Strong Buy) stocks here.

3 Medical Instruments Stocks With Potential to Outperform
Image Source: Zacks Investment Research

ShockWave Medical

ShockWave Medical has a Momentum Score of B. The Zacks Consensus Estimate for earnings has moved 12.1{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} and 4.1{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} north for 2022 and 2023, respectively, in the past 60 days.

The increased adoption of coronary IVL in the United States, continued sales force expansion, growing international expansion and higher adoption of Shockwave products are likely to boost the company’s performance. The company’s strong global growth highlights the significant clinical need for a better calcium treatment and how well the team at ShockWave Medical is addressing the same with IVL.

ShockWave Medical, Inc. Price

ShockWave Medical, Inc. Price

ShockWave Medical, Inc. price | ShockWave Medical, Inc. Quote

iRadimed

iRadimed has a Momentum Score of B. The Zacks Consensus Estimate for earnings has improved 2.9{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} for 2022 in the past 60 days. The consensus estimate for 2023 earnings stands at $1.20 per share, implying year-over-year growth of 13.2{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f}.

iRadimed is a leader in the development of innovative magnetic resonance imaging (“MRI”) medical devices and the only known provider of a non-magnetic intravenous (“IV”) infusion pump system and non-magnetic patient vital signs monitoring systems designed for use during MRI procedures. During the third quarter, the company reported 23{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} growth in revenues and 35{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} in earnings from the year-ago period. The company stated that significant demand for its IV pump and patient monitor product lines continued during the third quarter. The company has a strong bookings growth that continued to add to its extensive backlog and is likely to drive revenues for the remainder of 2022 and 2023.

iRadimed Corporation Price

iRadimed Corporation Price

iRadimed Corporation price | iRadimed Corporation Quote

Tactile Systems

Tactile Systems has a Momentum Score of A. The Zacks Consensus Estimate for loss has narrowed 12.6{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} for 2022. The consensus estimates for 2023 loss stood at 10 cents, implying a year-over-year improvement of 87.3{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f}.

The medical technology company develops medical devices for the treatment of chronic diseases at home. During the third quarter, it reported 24{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} growth in revenues and loss narrowed 35.3{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} year over year. Strong demand for its products during the quarter led the company to raise its revenue guidance by approximately 1.5{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} as measured at the midpoint of the guided ranges. Meanwhile, its settlement of a pending securities class action lawsuit earlier this month removed an overhang.

Tactile Systems Technology, Inc. Price

Tactile Systems Technology, Inc. Price

Tactile Systems Technology, Inc. price | Tactile Systems Technology, Inc. Quote

Zacks Names “Single Best Pick to Double”

From thousands of stocks, 5 Zacks experts each have chosen their favorite to skyrocket +100{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} or more in months to come. From those 5, Director of Research Sheraz Mian hand-picks one to have the most explosive upside of all.

It’s a little-known chemical company that’s up 65{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} over last year, yet still dirt cheap. With unrelenting demand, soaring 2022 earnings estimates, and $1.5 billion for repurchasing shares, retail investors could jump in at any time.

This company could rival or surpass other recent Zacks’ Stocks Set to Double like Boston Beer Company which shot up +143.0{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} in little more than 9 months and NVIDIA which boomed +175.9{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} in one year.

Free: See Our Top Stock and 4 Runners Up >>

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iRadimed Corporation (IRMD) : Free Stock Analysis Report

Tactile Systems Technology, Inc. (TCMD) : Free Stock Analysis Report

ShockWave Medical, Inc. (SWAV) : Free Stock Analysis Report

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The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.

Ensure your diet is heart-friendly by making these healthy changes

It is a well-known fact that heart health forms the core of overall wellness. It beats about 2.5 billion times over the average lifetime and pushes millions of gallons of blood to every part of the body. This steady flow carries with it oxygen, fuel, hormones, nutrients, other compounds, and a host of essential cells. It also whisks away the waste products from metabolism.

“As such, many essential body functions fail in case the heart stops functioning, with some stopping almost instantly. It can also fail when its health is compromised by way of a poor diet and lack of exercise, smoking, alcohol, infection, and more. A healthy lifestyle, especially when started at a young age, goes a long way to preventing cardiovascular disease or any other disease or illness,” said Anam Golandaz, clinical dietician, Masina Hospital, Byculla, Mumbai.

The expert went on to share certain important points that will help aid heart health.

Path to improve heart health

Following these nutritional strategies can help you reduce or even eliminate some risk factors, such as reducing total and LDL (low-density lipoprotein)-cholesterol; lowering blood pressure, blood sugars and triglycerides; and reducing body weight.

Control your portion size

Overloading your plate, taking seconds, and eating until you feel full can lead you to eat more calories than your body requires. “These extra calories will make you put on extra weight and lead to you being overweight and obese — the main causes of heart diseases. Follow a few simple tips to control food portion size – Use a small plate or bowl; eat more low-calorie, nutrient-rich foods such as fruits and vegetables, and eat smaller amounts of high-calorie, high-sodium foods, such as refined, processed, or fast foods.

heart health Ensure your prevent heart related health scares by these diet tips (Source: Getty Images/Thinkstock)

Be smart about fats

Unlike widely believed, some fats are actually good for us and our hearts. When using fats for cooking, choose monounsaturated fats such as olive oil or canola oil. Also, a good source of monounsaturated fats are avocados. Polyunsaturated fats (found in nuts and seeds) and omega-3 fatty acids (found in fish such as tuna and salmon) are also healthy choices. In general, try to avoid trans fats that are usually found in processed foods and snacks such as bakery products, or packed food. Look for the words “partially hydrogenated” in the ingredient label to know whether a food item contains trans fats.

What’s the difference between healthy fat and unhealthy fat?

Saturated and trans fats can be harmful to your heart and arteries. A basic rule of a heart-healthy diet is to lower these harmful fats but include moderate amounts of healthy fats such as mono- and polyunsaturated fats, especially omega-3 fats. These are good for our hearts.

Go whole-grain

Whole-grains such as wheat, oats, buckwheat or wholegrain breads or pastas are higher in fibre, magnesium, manganese, selenium, B vitamins and complex carbohydrates. Choose them over white breads or regular pastas.

Eat plenty of fruits and vegetables

They contain fibre, antioxidants ,vitamins, and minerals that are good for our heart and overall body.

Prepare meat healthily

Instead of deep frying, try baking, broiling, and roasting as these are the healthiest ways to prepare meat and poultry. Also trim any outside fat or skin before cooking.

Don’t forget beans

Dry beans, peas, soybean and lentils are good source of protein and fibre. They are also high in minerals without the saturated fat found in some animal proteins. Eating beans as part of a heart healthy diet and lifestyle may also help to improve blood cholesterol, a leading cause of heart disease.

Choose low-fat dairy

Go for fat-free or low-fat versions of milk, yoghurt, and cheese products as it is high in saturated fat.

Include lean protein

Eat protein–rich foods, including fish, lean meats, skinless poultry, eggs, nuts and seeds, and beans.

What should you avoid eating?

A heart-healthy diet limits some nutrients. These include no-salt seasonings instead of salt.
Packaged foods, sauces, canned foods, and processed foods contain a high amount of sodium.
Sweetened drinks, snacks, and sweet treats are the main source of added sugars in our diet. These include sodas, sweetened coffee and tea, energy drinks, cakes, pies, ice cream, candy, syrups, and jellies. Limit these types of foods and drinks.

Limit your intake of alcohol. Too much alcohol can raise blood pressure and cause weight gain. It can also contribute to or worsen heart failure in some people.

“Know that no single food can make you healthy instantly, so your overall dietary pattern is more important than specific foods,” said Golandaz

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How to Keep Your Heart Healthy Through Your Diet

Heart disease is a leading health issue in the US. When it comes to your risk level, some factors are out of your control — like, say, your blood type. But other factors are more changeable, including your diet. Everyone from the American Heart Association to the US Department of Health and Human Services recommends making specific food choices to support a healthy heart. Because foods for heart health can reduce other potential cardiovascular issues — like high blood pressure and high cholesterol — it’s worth keeping in mind as you plan your weekly meals. 

Keep reading to find out which foods to look for and what a heart-healthy diet looks like overall.


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What is a heart-healthy diet?

Studies have revealed two things: foods that are riskier for your heart and foods that strengthen it. Fortunately, you’re not about to get hit with a bunch of curveballs. The best foods for heart health are ones you probably already think of as healthy. Similarly, the not-so-heart-healthy foods are probably already on your radar for not doing your body any favors.

Before we dive in here, let’s say: everything in moderation. Unless you already know you have a heart health issue, you don’t need to cut out any foods or make drastic changes. We’re not saying you can never have another piece of bacon or crack open another soda. Instead, being mindful of what a heart-healthy diet looks like can help you incorporate more of those foods into your meals.

Now, let’s talk details. According to the AHA and Department of Health, a heart-healthy diet is rich in:

  • Produce
  • Lean proteins
  • Fiber-rich complex carbs
  • Healthy fats

A diet full of colorful fruits and vegetables, whole grains and healthy proteins and fats will give your body the fiber, vitamins and minerals it needs to support a healthy heart. 

A bright rainbow spectrum of produce on a platter.

David Malan/Getty Images

Conversely, if you’re trying to boost cardiovascular health, you want to limit your intake of:

  • Trans fats
  • Saturated fats
  • Processed meats (for example, lunch meat, salami and hot dogs)
  • Excess salt
  • Excess sugar
  • Refined carbohydrates (for example, white breads and snacks)
  • Red meat
  • Excess alcohol

If a lot of your favorites are on the less heart-healthy list, don’t panic. You can still include them in your diet (unless your doctor says otherwise). Just make sure that these foods aren’t taking over every meal, and try to add as many heart-healthy foods into your day as you can.

Heart-healthy foods

Person in a long brown dress browses a grocery store aisle.

d3sign/Getty Images

If you want to feel good about what your next grocery trip will do for your heart health, you can grab items in these specific categories.

1. Fruits and vegetables

Remember the food pyramid from back in the day? It was on to something. Your body benefits from eating quite a bit of produce.

That’s because veggies and fruit load in a lot of nutritional density per bite. Bananas and sweet potatoes deliver potassium, a key mineral for heart health. Cruciferous veggies may help to prevent clogged arteries. Leafy greens deliver fiber, which can help to lower cholesterol and blood pressure. 

Long story short, the more produce you’re packing in, the better. And if fresh produce doesn’t work for your budget or your lifestyle, don’t worry. You can get plenty of nutritional benefits from frozen, dried and canned options. Just make sure they’re marked low-sodium. 

2. Whole grains

Not all carbs are bad. Refined carbs like the ones in white bread fly through your body, usually doing you more harm than good. But complex carbohydrates, like the ones you’ll find in whole grain products, deliver fiber, which we’ve already mentioned as a heart health booster. 

Plus, they often come packed with vitamins and minerals like iron, selenium, thiamin (Vitamin B1), riboflavin (Vitamin B2), niacin (Vitamin B3), folate (Vitamin B9) and magnesium. If you’re looking for a heart-healthy diet, choose products that have whole grains in their ingredient list. Plus, complex carbs can also be found in beans, potatoes, peas and corn.

Fish tacos on a plate, with corn tortillas and fresh cilantro.

GSPictures/Getty Images

3. Lean and plant protein

While certain proteins — like red and processed meat — can be hard on your heart, others top the list of foods for heart health. The key here is to look for plant-based protein, lean animal proteins and fish. Experts recommend mixing up your protein sources. So you have plenty of options, stock up on:

  • Lentils
  • Beans
  • Nuts
  • Seeds
  • Tofu
  • Fish, especially ones high in omega-3 fatty acids
  • Eggs
  • Low-fat dairy products
  • Poultry
  • Seeds

Swap some of your red meat and cured pork for the options above and you’ll be doing your heart a favor. 

4. Healthy fats

You might think that fat spells heart trouble, but it’s all about the type of fat. While trans and saturated fats have been linked to cardiovascular issues in numerous studies, your body, including your heart, needs healthy fats. You can get these from fish, nuts and seeds, along with avocados and moderate amounts of plant oils like:

  • Olive oil
  • Sesame oil
  • Sunflower 
  • Soybean oil
  • Canola oil
  • Corn oil
  • Safflower oil

As a general rule of thumb, if the fat would be solid at room temp, it’s probably saturated. If it would be a liquid, it most likely falls under the unsaturated variety. Think butter (controversial for health) versus olive oil (definitely part of a heart-healthy diet). 

Sesame oil pouring into a small dish.

SUNGMIN/Getty Images

5. Heart-check foods

The American Heart Association has certified certain foods for heart health and given them the Heart-Check seal, which you can find on some food packaging. Once you learn that seal, it can make it easier to stock your cart with foods for heart health. 

For the best results, pair your heart-healthy diet with other heart health boosters like regular exercise, sleep and stress management techniques. It can also be helpful to learn your blood type and what it means for your risk of specific cardiovascular conditions. 

The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.

How therapists are trying to heal intergenerational trauma : Shots

How therapists are trying to heal intergenerational trauma : Shots
Culturally responsive therapy is a growing trend, as therapists of color try to make counseling more inclusive.

Cambodian American Eden Teng was was born in a refugee camp on the border of Thailand and Cambodia just a few years after the Cambodian genocide. She moved to the U.S. with her mom and aunt when she was 6.

Teng attributes much of her own resilience in transitioning to the U.S. to her exuberant mom, who wore whatever she wanted and wasn’t afraid to defy social norms — even when it was embarrassing for a teenage Teng.

But when she was growing up, Teng also witnessed the negative impacts of historical, racial and intergenerational trauma on her mom’s wellbeing. Teng often felt confused by the way her mom’s emotions could spiral out of control for seemingly no reason, or why why she had so many health problems.

When Teng first encountered psychology in college, she realized that her mother’s past was directly connected to her emotional and physical health. (Scientists are learning that stress and trauma are sometimes linked to chronic illnesses, like hypertension, diabetes and kidney disease.)

It was this realization that compelled Teng to become a therapist; in 2018 she began her graduate studies in Seattle.

But when COVID-19 hit and the Black Lives Matter movement came into full force, with communities of color having a more public conversation about their struggles in the U.S., Teng says she started feeling differently about her training and the profession she’d be entering. She began to notice how dealing with certain issues, including race and immigration, were not given priority in her clinical training — even though she knew how important they are in shaping a life.

“I didn’t feel represented, and I felt that so much of my family’s history just didn’t feel like it was considered,” she says, adding that she was studying under teachers who were predominantly white. “I just felt silenced in my own history [and] my own experience in the work that I was doing.”

Teng’s graduate program isn’t the only one like this. Therapy is a predominantly white field in the U.S. — 80{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} of psychologists, 63{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} of counselors and 59{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} of social workers are white, according to Data USA, a website that constructs visualizations of public federal data.

Many of the founding ideas, techniques and schools of practice of therapy were developed by white scholars or practitioners. As a result, the field has marginalized the experiences of people of color, therapists and patients say. Microaggressions are also pervasive in psychological practice, researchers note, and many immigrants report not attending therapy because of language barriers, a lack of insurance and high costs.

That’s why Teng wanted to take a new approach. For her, that meant joining a growing movement of other counselors hoping to transform the practice of therapy, to make it more accessible and relevant to people of color and — ultimately — to help them find healing.

Embracing a practice of ‘decolonizing therapy’

Teng was initially inspired by people like Dr. Jennifer Mullan, who refer to this work as “decolonizing therapy,” a process of addressing the structural racism and other forms of oppression that keep therapy from serving many marginalized communities.

“I think the best way to describe decolonized therapy is that it is really making space to examine the external pressures, stressors, and layers of oppression that my clients have endured and survived,” Teng says.

She gives the example of microaggressions in the workplace, or job interviews. “There are opportunities that are not given to you because of your identities,” she says, “But if we look at it through the lens of self-esteem, it’s like ‘Something is wrong with you. You just need to think better about yourself,’ right? Like you need to be more positive.”

But for people of color, that framework of just being “more positive” doesn’t always work. It doesn’t account for racism, xenophobia and other forms of discrimination directed toward them. “The challenge,” Teng explains, “is to recognize that how you’re feeling about yourself can also be internalized oppression.”

Teng’s practice in decolonizing therapy digs into family history, helping her clients of color better understand how the historical oppression of their ancestors affects them. She says this is true for people from her own community, who experienced the genocide when the Khmer Rouge regime killed about 2.2 million people. “When we’re talking about Cambodian refugees and immigrants, there’s a history here that is so horrific, rich, and devastating.”

Teng finds children of Cambodian refugees who have been through the genocide can struggle with guilt. “In first-generation or second-generation Cambodian Americans, there’s this experience that your parents have sacrificed or have gone through so much,” she says. “They’ve experienced tremendous loss. And having that sense of their sacrifices, we feel we need to hold that harm and that grief and that pain.”

Holding onto a parent’s pain leads into tricky territory, says Teng. “We also feel that we have to transcend it by being perfect or striving to be so successful that we are becoming millionaires … versus really being with the gentleness of the grief, and the emotions that are being held and passed down.”

Using culturally responsive techniques

To respond to these issues, Teng has developed a few approaches that are different from the way she was trained. First, Teng often brings in the family to her practice.

“This may mean that we involve parents in sessions so that we can hear from their point of view,” she says. “When we’re in that space, there are a lot of opportunities to shed light on the impacts of being a child of immigrants. And through that lens — of being someone like a first generation immigrant — we can discuss the harm that is very much connected to the harm that parents have navigated.”

Teng supports the children and parents in openly discussing experiences like racism and genocide in a secure and validating environment. She says many who survived the genocide, had to suppress their feelings. “And so, when you have the experience of suppressing those [painful] emotions, you’re also suppressing joy and connection, belonging.”

Allowing her clients and their parents to experience the full spectrum of emotions can be healing, she says. “[They] can allow for positive attachments and relationships that feel meaningful.”

Teng also works against the stereotype of the detached therapist-as-expert. She makes clear to her clients that she may not have all of the answers, and prefers to be transparent with her clients about her own intergenerational trauma. “When we can really be with what’s hurting, we know we’re together in this,” she says. “I’m a part of this collective healing journey with my clients.”

Growing acceptance of the role of historical trauma

Like Teng, Ramona Beltran became interested in decolonizing therapy because of the issues she was seeing in her community of origin. She identifies as Xicana of Yaqui and Mexica descent and is a professor of social work at the University of Denver.

When she was at the start of her career, several of her family members passed away before they reached 60 years old and she found herself asking what the links are between her community’s history of trauma and their health.

When Beltran entered a doctorate program to study historical trauma 20 years ago, she wasn’t taken seriously at first, she says — such as when she gave some presentations on the theoretical framework of historical trauma and healing. “I remember this one [presentation] where they forwarded me the feedback, and several people were like, ‘This is political. It’s ideological. It doesn’t count as research. There’s nothing empirical about this. This isn’t like real academic work.'”

Now, Beltran says things have changed, “I teach a whole class on historical trauma and healing, and it’s always one of the classes that gets filled up right away,” she says. “And that, to me, is progress.”

When she was working on her master’s degree in social work, she says, she noticed that all of the evidence-based styles of practice she had learned in grad school weren’t enough.

“They were just like these kind of mainstream approaches to therapy that were generated from, primarily white, primarily middle class families,” Beltran remembers. “And so maybe they would be translated into Spanish, but to me, what I was seeing was that those practices weren’t really generating a lot of healing.”

Now when she teaches, Beltran emphasizes that decolonizing can take different forms, depending on the experience of the therapist and the shared experiences of the community the therapist is trying to reach.

She highlights three key aspects of culturally responsive therapy: building authentic relationships, ensuring community representation, and re-connecting with one’s cultural background. Like Teng, Beltran is especially interested in working with clients to help them see their culture as a form of intergenerational strength, rather than suffering.

A growing need for culturally responsive therapy

While therapists like Beltran and Teng are committed to making therapy more inclusive, communities of color continue to struggle with getting access to therapists. Teng gets a lot of people contacting her who she simply cannot help. “I’m only licensed to see folks in my area, and there are so many that are interested. And it breaks my heart every time, where I’m not able to provide support.”

She notes that this is especially common for clients living in areas with few clinicians available. “I had one from Kansas most recently, who was like, ‘We don’t have any Khmer therapists anywhere in the state.’ But, unfortunately, I’m not able to provide that service.”

Teng knows what it’s like to lack access to therapy. “I myself haven’t had a therapist of my own who practiced the way that I do until most recently,” she says.

But there have been some recent moves in the right direction, Teng says. Organizations like Inclusive Therapists created the BIPOC Therapy Fund to provide financial help for at least four initial sessions for people of color seeking therapy. The Asian Mental Health Collective also created the Lotus Therapy Fund to provide financial support to Asian therapy seekers for eight sessions.

And the largest professional organization of psychologists in the U.S. is also promising to make changes. Last year, the American Psychological Association issued a formal apology for its role in what it called “promoting, perpetuating and failing to challenge racism, racial discrimination and human hierarchy in the U.S.“

The APA promised to support more research centered on non-Western perspectives, provide more access to culturally competent training, and create more opportunities for people of color to enter the field of psychology. This August, the organization committed $1.1 million to a new Racial Equity Fund to carry out these three goals.

Teng says she hopes to see more funds dedicated to helping people of color get access to therapy that recognizes their history and experiences.

“There’s no way that we can just say that we’re going to look at this from a cultural lens without actually looking through the historical, intergenerational lens,” she says. “And so, it has to be comprehensive and interconnected for it to truly honor the human being that is in front of you.”

The troubling legacy of a Black woman’s cells

Ethical concerns over her cells, the most widely used in research, are in the spotlight as family seeks reparation

The troubling legacy of a Black woman’s cellsIn the opaque world of scientific research, HeLa cells are legendary. These cells mark one of the most significant milestones in the history of modern medical research, because it was the first time in decades that scientists were able to keep human cells alive in culture.

While other cells died eventually, HeLa cells were amazing: they reproduced every 24 hours and never stopped doing so, thus becoming the first immortal cells grown in a laboratory.

They have been used in research over a wide spectrum and were instrumental in developing drugs for an astonishing range of diseases, from influenza and herpes to leukaemia and Parkinson’s.

Jonas Salk’s life-saving polio vaccine would not have been possible without HeLa cells. And they also became a multimillion-dollar industry for some companies.

Yet, for decades, the racial origin of the most famous human cell was kept hidden from the world—and from her family.

The remarkably prolific and resilient cells were taken from the cervical tumour of a young Black woman, Henrietta Lacks—hence the name HeLa—who was being treated at Johns Hopkins Hospital in Baltimore, US, for a virulent form of cervical cancer.

Lacks was a young mother of five when she died in 1951 at the age of 31. Her cells were collected by George Gey, a prominent cancer and virus researcher, who ran a nearby tissue laboratory.

Lacks did not know that her cells were being taken for culture, nor was her’s or her family’s permission sought before or after her death.

It was not until 1981 that the origin of HeLa was credited to her, and her family learned of this by accident. This and the subsequent story of how her family was used for further research, again without their knowledge or consent, has sparked a debate on an individual’s right over their genetic material and also the ethics over its use by researchers and commercial organisations.

There is also a lawsuit by Lacks’ heirs, who are seeking compensation from laboratories that made millions from the sale of HeLa cells. For a start, they have filed a case against Thermo Fisher Scientific, accusing it of selling Lacks’ cellular material, developing and manufacturing cellular products incorporating HeLa cells, and seeking intellectual property (IP) rights on them.

This implies they are staking IP rights on her genetic material. The nub of the case is that the company appropriated Lacks’ genetic material for its own gain without payment, permission or approval from the Lacks Estate or family.

The family had previously sought payment from Johns Hopkins and the suit against Thermo Fisher mentions “the unlawful conduct” of its doctors. Johns Hopkins is categorical that it has “never sold or profited from the discovery or distribution of HeLa cells” and does not own the rights to the cell line.

“Rather, Johns Hopkins offered HeLa cells freely and widely for scientific research.” The controversial point here is whether the hospital and Gey acted unethically or illegally in taking tissue from Lacks’ cervical tumour.


Read


The hospital says that at the time, tissue samples were drawn from all patients regardless of race and socio-economic status, and no formal consent was required. The institution points out that it was one of only a handful to have treated poor African-Americans in the early decades of the last century.

Johns Hopkins has made some amends by naming a building on its campus after Lacks, because it acknowledges “the HeLa cell line has been critical to numerous advances in medicine.”

Other institutions have made monetary reparation. A high-profile six-figure donation (exact amount was not disclosed) was made by Howard Hughes Medical Institute to the Henrietta Lacks Foundation in 2020.

The institution said it was done to “acknowledge Henrietta for the use of HeLa cells and to acknowledge that the cells were gained inappropriately”. Observers are hoping the gesture by the institution, which is a major funder of basic biomedical research, will set an example for other research outfits.

The HeLa case came into public focus only after Rebecca Skloot published The Immortal Life of Henrietta Lacks, a personalised memoir and scientific account of the life and afterlife of the Black woman who made the most significant contribution to the fight against a host of diseases.

The book, which highlighted racial discrimination and exploitation of African-Americans, was made into a film starring Oprah Winfrey. Skloot also set up the foundation, which gives grants to people who have unknowingly been part of historic medical research studies and to their families who did not benefit from the work.

It supports families of Black men who, from 1932 to 1972, were part of a callous US government experiment to observe the effects of untreated syphilis. The men were given placebos and sham treatment but were told they were receiving free healthcare.

World Health Organization (WHO) chief Tedros Adhanom Ghebreyesus has done much to make reparation and to highlight the inherent racial and other inequalities in medical care.

Over the past year, he has bestowed the WHO Director-General’s Award on Lacks in recognition of the “world-changing legacy of this Black American woman” and more recently on October 16, he appointed the Lacks family as WHO Goodwill Ambassadors for Cervical Cancer Elimination. The appointment is a recognition of their efforts to champion cervical cancer prevention and to preserve the memory of their ancestor.

In a stark reminder of persistent inequities, Ghebreyesus noted that Lacks’ cells were foundational in the development of human papillomavirus (HPV) vaccines that can eliminate the same cancer that took her life, and yet in countries with the highest burden of cervical cancer, these vaccines were not adequately available.

So, too, with COVID-19 therapies and many other life-saving innovations developed with the miraculous HeLa cells. Although the cells were used in COVID-19 research, tools to stop the disease are not being shared with low- and middle-income countries.

He would, or should, have made scientists and research organisations uncomfortable when he pointed out how much some people benefited from the cells.

“Fortunes have been made, science has advanced, Nobel Prizes have been won and most importantly, many lives have been saved. No doubt, Henrietta would have been pleased that her suffering has saved others.”

Tedros said by honouring Lacks, WHO acknowledges the importance of reckoning with past injustices and advancing racial equity in health and science. In this, he was endorsing the call of many that science must right historical wrongs of the past. Nothing must be taken from a person without consent.

This was first published in the November 16-30, 2022 edition of Down To Earth 





The Healthcare Freedom Act is a vital solution to runaway medical debt

As the pandemic lingers, contributing to rising inflation and looming economic recession, Americans from all walks of life may be concerned about their medical bills. 

The Healthcare Freedom Act, proposed by Rep. Chip Roy (R-Texas), seeks to help Americans regain control of their healthcare expenses by creating “health freedom accounts” similar to existing health savings accounts. Health savings accounts enable patients to save pretax dollars for future medical expenses, but are limited to only those with high-deductible health plans, and contain numerous restrictions on what types of healthcare spending may qualify. Roy’s bill would allow any American, regardless of their health insurance type, to become eligible for health freedom accounts, as well as expand the list of qualified medical expenses. 

As a physician, I call upon Congress to pass this legislation in order to provide patients greater autonomy over their healthcare. 

Health savings accounts were first established in 2003 as part of the Medicare Prescription Drug Improvement and Modernization Act and became more prevalent as more employers began offering high-deductible health plans over the past 20 years. Many patients with high deductible plans never meet their annual deductible, and thus are forced to rely on money from their health savings account to cover routine health expenses; for these individuals, any money spent on insurance premiums by themselves or their employer is wasted. To make matters worse, current regulations also prohibit the use of health savings accounts to pay for insurance premiums. These policies serve only to enrich insurance companies at the expense of patients and private employers.  


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The Healthcare Freedom Act is a vital solution to runaway medical debt

Currently, HSAs allow maximum family contributions of up to $7,300 per year to a tax-deductible account, which enables the contributions to be untaxed for that year. In addition, the money grows tax-free and may be withdrawn from the account untaxed. These tax-protective mechanisms are how HSAs came to be known by the coveted descriptor “triple tax-free.” In addition to allowing all Americans to obtain an HSA/HFA, the Healthcare Freedom Act would nearly double the yearly contribution limit to $12,000, and allow individuals 55 years or older to contribute an additional $5,000. These changes are necessary due to the rapid growth in healthcare costs which routinely outpaces the already-astronomical rate of inflation.  

The Healthcare Freedom Act would also expand the list of approved medical expenses to include insurance premiums, direct primary care physician subscriptions, and payment to Healthcare Sharing Ministries. The bill would enable money from HSAs to be spent on all of these, plus additional services that may not be covered by health insurance. For example, patients coming to dermatology clinics may use money from their HSA/HFA to pay for the removal of benign skin lesions or other procedures deemed as “cosmetic” by insurance companies.  From the physician side, it allows a wider range of practice possibilities that would enable doctors to practice more personalized medicine.  

If HFAs become commonplace, more patients will be able to obtain their medications through compounding and specialty pharmacies, cutting out middlemen and reducing costs. Indeed, physicians will be able to circumvent insurance headaches such as step therapy (requiring patients to fail certain categories of medications before insurance will cover alternative therapies) if patients can pay for their medications directly. As a dermatologist, I frequently use direct-to-consumer pharmacies to help patients obtain customized therapies for their skin. 

Healthcare freedom accounts would expand access to these services to patient populations who may not have the financial ability to pay for these treatments out-of-pocket. Employers may also like the added flexibility of HFA’s, as they would be able to offer the new health savings account as an employee benefit without being forced to subscribe to a group high-deductible health plan. 

The net effect of expanding the number of approved expenses would be increased patient and physician autonomy. From the patient side, the Healthcare Freedom Act allows them to spend their hard-earned savings in a way that most aligns with their values. 

As a physician, I look forward to serving patients based on the ideals of the Hippocratic Oath rather than following arbitrary guidelines created by insurance companies.  

Aamir Hussain is a resident physician practicing in Washington, DC. Rufus Sweeney, a medical student at the University of Wisconsin, assisted in the creation of this story.