The Most Interesting Nutrition Products and Supplements of 2022

This story is part of our end-of-year series This Year in Gear, rounding up the most notable releases of 2022.


To create and sustain a worthwhile fitness journey, you need to have a proper nutritional plan as well. From keeping your muscles fueled, to maintaining focus and energy, there’s a lot of products that go beyond your basic daily meals (as important as those are, too).

There are a number of nutritional powders, pills and other products that can boost your wellness in a number of ways, and this year saw a great deal of inventive, effective releases within the space. From high-octane pre-workouts, to sustainable meal replacements, gut-boosting dailies and more, here are some of our favorites that made healthy living a little more approachable in 2022.

Natreve Mooless Animal-Free Whey Protein

The Most Interesting Nutrition Products and Supplements of 2022

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Whey protein is a foundational supplement, but for those following animal-free diets for health or moral reasons, this pivotal powder has been off-limits for years. That is, until Natreve shook up the supplement industry earlier this year with the launch of Mooless, a first-of-its-kind animal-free whey protein powder that utilizes microflora for the sake of creating tasty, nutritious shakes. The microflora, courtesy of Perfect Day, are given an exact copy of the DNA sequence corresponding to cow’s milk protein, allowing for a more sustainable manufacturing process that cuts back on water consumption, greenhouses gas emissions and energy usage.

Price: $30

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Momentous Collagen Shot

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Prime for on-the-go supplementation, these all-new single-serving packets from Momentous can make taking care of your joints, hair, skin and more a breeze. We like the convenience of the gel pouches, allowing for quick pickup that doesn’t require you to mix a shake or tote around a hefty pill bottle. Plus, the flavor is nice, albeit after you get used to the gel consistency. Each box contains 15 individual packets delivering 10 grams of collagen peptides, which is a respectable dosage, too.

Price: $42

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Huge Supplements Wrecked Enraged

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The original Wrecked from Huge Supplements is our go-to pre-workout for sparking up our focus and energy before training. Still, though, there are days where you need a little more stimulants in your mix to power through your circuits. Enter Wrecked Enraged, the brand’s high-stim pre-workout boasting 200mg of caffeine per scoop. Available in two tantalizing flavors, this pre-workout also comes in a 40-serving tub, which can be great for stocking up for over a month’s worth of high-octane training.

Price: $45

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Mikra CELLF

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Every time you stress your body, you cause damage to your cells. And as the wear-and-tear piles on with age, you become less able to fight off new stresses, whether they come from a taxing workout or late night out on the town. This is the exact dilemma Mikra’s CELLF aims to target, using clinically-tested formulas with the goal of preventing cellular breakdown. Single-serving packets make daily supplementation much easier, and the effects can be recognized rather quickly over routine use. If you’re looking for an innovative way to repair your cells for the sake of improved cognitive function, boosted energy, better sleep and more, this is the nutritional add-on for you.

Price: $98

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Everlywell Multivitamin Gummy

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Adding a multivitamin to your daily routine can help you ensure you’re getting adequate doses of necessary vitamins and minerals. One of the newest additions to this supplement category comes from Everlywell, a brand best known for its at-home test kits covering food allergies, food sensitivity and other nutrition-based inquiries. Each chewable gummy contains hearty doses of key micronutrients including vitamin A, vitamin B5, vitamin B6, vitamin B12, vitamin C, vitamin D, vitamin E, biotin, folate and more. Plus, each bottle contains enough doses for a month’s worth of flu-busting goodness.

Price: $25

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Optimum Nutrition Gold Standard 100{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} Plant Based Protein Powder

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Serving as one of our favorite vegan protein powders for muscle-boosting support, this latest product from Optimum Nutrition is a great addition to the brand’s “gold standard” lineup. Per serving, you can expect to take in 24 grams of protein, plus 8.4 milligrams of iron — an often difficult vitamin to acquire through a vegan diet. 150 calories is also a decent meal replacement for those unable to sit down for a more prepared dish. We recommend mixing with oat or almond milk to give each sip an enjoyable nutty taste.

Price: $35

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Gatorade Gummies

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Gatorade has long been a trusted source for keeping our bodies fueled and ready to go for a bevy of physical activities. But earlier this fall, the brand dove a little deeper into that notion with the launch of two Gatorade Gummies. These tasty chewables were formulated with scientists from the Gatorade Sports Science Institute to deliver key vitamins and nutrients, each with their own performance benefits. The cherry-flavored Recovery Gummies feature hearty doses of tart cherry powder and vitamin D to help with post-workout cooldowns, while the citrusy Immune Gummies deliver helpful notes of vitamin C and zinc, ideal for flu season and improving your body’s defense system.

Price: $47

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Athletic Brewing Athletic Lite

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Athletic Brewing Co

Okay, so beer might not be the most health-oriented beverage, but don’t tell that to the innovators over at Athletic Brewing Company. The brand’s lineup of tasty non-alcoholic concoctions has been on our radar for a while, but we were really intrigued with the recent drop of the all-new Athletic Lite. Serving as a great NA alternative to your favorite cheap beer, this brew is intended to be a go-to daily option with clean, crisp flavor notes and just 25 calories. As the trend of reducing alcohol intake continues with each passing year, we’re more than happy to sit back and relax with this tasty sipper for a well-deserved reward post-training.

Price: $14 (6 pack)

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Liquid IV Hydration Multiplier+ Probiotic Kombucha

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Staying hydrated is a key factor to living a healthy lifestyle, and so is maintaining a proper microbiome. There are many ways you can target your gut health, but why not let a convenient, on-the-go supplement multitask for you? Liquid IV — makers of some of our favorite hydration-boosting powders — can tackle all the above thanks to the brand’s newest lineup of Hydration Multipliers containing probiotic-filled kombucha. These latest packets rely on a synergistic blend of 1 billion colony forming units (CFU) of the trademarked BC30 Probiotic as well as fermented tea vinegar powdered kombucha to deliver tasty beverages that can quench your thirst and boost your gut on the fly.

Price: $25

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Ritual Synbiotic+

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While kombucha-filled powders can be a great way to supplement your gut health, we understand they’re not for everyone. Yet, there’s still nutritional alternatives out there, like Ritual’s latest innovation — Synbiotic+. These daily capsules require zero refrigeration, which makes storage more convenient, and the probiotic blend contains 11 billion colony forming units from two of the world’s most clinically-studied strains of microbe: BB-12 and LGG. Plus, Ritual stands behind its product and outlines each and every ingredient with transparent, detailed information, even down to the supplier and the ingredient’s final location of manufacturing.

Price: $54

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Verb Caffeinated Snack Bars

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Need a quick boost but don’t want to fire up the espresso machine or shake up a pre-workout powder? These new, all-natural, plant-based snack bars from Verb can provide the same amount of caffeine as your normal morning cup of Joe, with the added perks of protein, carbohydrates and a mix of helpful vitamins. Available in a number of mouth-watering flavors, these can be a great alternative to finding energy throughout the day, especially for those wanting a different source from a traditional pot of coffee.

Price: $29

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Zoa+ Pre-Workout Energy Drink

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With 200mg of natural, clean caffeine from green tea extract and green coffee per can, this canned concoction from the people’s champion can really lay the smackdown to your tired, sluggish state. Our favorite canned pre-workout is also convenient for traveling athletes, as there’s no shaker or tub required to reap the benefits of this tasty beverage. Plus, Zoa+ also delivers B Vitamins, Gingko Biloba, 3,000 mg of performance-lifting L-citrulline and vitamins C and D for a slew of fitness-related benefits. So, whether headed to the gym, the track or the squared circle, consider this concoction for a clean boost of energy and focus.

Price: $40

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2022’s most interesting health care research papers, according to the experts

Though the pandemic and all its attendant health care crises remained the major health care story of 2022, churning all the while in the background has been the critical work of academic scholars, operating on longer timelines, who are still trying to make sense of US health care and of medicine itself, to get a better idea of what’s wrong and how to make it better.

To wrap up this year, I asked a couple dozen health policy experts what research released this year (though, as one of them reminded me, these papers are often years in the making) had surprised them, changed their thinking, or struck them as especially notable.

Here are five particularly interesting papers, at least in my view. Because many more than that warrant mention, I have tried to cram in as many references to other work as I could. One of my lessons from this exercise was that there are noteworthy new studies being produced all the time. The US health system certainly merits such extensive investigation, given the number and diversity of its flaws.

These studies cover a broad range of subjects, from the intricacies of Medicaid provider networks to prescription uptake by Medicare beneficiaries to how bystanders react when a person experiences a cardiac episode in public. But first, on the topic of the pandemic…

1) Vaccination education campaigns in nursing homes didn’t make much difference

Several experts pointed me to data sets related to Covid-19 vaccination in nursing homes, the scenes of so much illness and death in that frightening first year of the pandemic. Larry Levitt, executive vice president of the Kaiser Family Foundation, flagged one recent KFF survey that found less than half of nursing-home residents are up to date on their vaccines.

That put into sharp relief the findings of a study that Harvard Medical School’s David Grabowski cited as one of his favorites of the year. The paper, published in JAMA Internal Medicine in January 2022, evaluated an effort to use educational campaigns and other incentives to improve vaccination rates among residents and staff in nursing homes.

They did not find a meaningful effect, despite three months of programming. There was plenty of room to grow, particularly among the staff, roughly half of whom were unvaccinated during the study period. (Vaccination rates among residents were already high at the time, though the experiment still did not find a significant effect of the multi-faceted campaign.)

“The conventional wisdom was that a big part of lagging vaccination rates was a lack of information and knowledge about the benefits of vaccination,” Grabowski said. But this study found instead that “these educational efforts were unsuccessful at encouraging greater vaccination. Although information campaigns sound like great policy, they really aren’t.”

He lamented that the study had been ignored by policymakers, noting federal efforts to increase vaccination rates among this population remain focused on education. Grabowski said the policies with the strongest evidence are vaccine clinics and vaccine mandates for staff.

2) Medicaid’s “phantom” networks may overstate patients’ access to health care

I love good jargon, and “ghost physicians” is one of my favorite new phrases of the year, which was recently brought to my attention by Harvard University professor (and former Vox contributor) Adrianna McIntyre.

It comes from this May 2022 Health Affairs paper, authored by Yale University’s Avital Ludomirsky and colleagues, which evaluated the provider networks of Medicaid managed-care plans. Those are privately administrated plans for low-income people that must follow state and federal Medicaid rules; they have grown in enrollment in recent years, with more states deciding to outsource their role in providing health coverage for the most vulnerable.

One of those rules is that enough doctors and hospitals accept those Medicaid plans, otherwise known as network adequacy. The Health Affairs study examined managed-care plans in four states over several years to get a better sense of providers’ participation in the program.

Their most striking finding is that while nominal participation was fairly high, about one-third of providers who technically accepted Medicaid actually saw less than 10 Medicaid beneficiaries in a given year. The responsibility for providing care to these patients was concentrated among a small number of practices, with 25 percent of primary care doctors providing 86 percent of the care and 25 percent of specialists providing 75 percent of those services.

In other words, while plenty of doctors might say they accept the plans, people who are enrolled in them may in practice find they have relatively few doctors to choose from. “Our findings suggest that current network adequacy standards might not reflect actual access,” the authors wrote in their conclusion. “New methods are needed that account for beneficiaries’ preferences and physicians’ willingness to serve Medicaid patients.”

The move toward more Medicaid-managed care has spurred a lot of debate and study. Matthew Fiedler, senior fellow at the Brooking Institution, sent me a Harvard study with its own surprising finding: In Texas, transitioning Medicaid enrollees to managed care had actually led to an increase in the use of prescription drugs and outpatient services, while the number of avoidable hospitalizations fell.

What seems to have happened, Fiedler said, is the state had been “penny-wise, pound-foolish” when running the program itself by imposing an unusually strict cap on the number of prescriptions patients could fill in a year. With that cap relaxed under the managed-care plans, patients filled more prescriptions and that corresponded to fewer episodes in which they ended up in the hospital when they didn’t have to.

Fiedler thought the study could also have implications for Medicare Advantage as well, another version of a government health insurance program that is being administered by private companies.

“To be clear, in many of these cases, it might well be better to fix this problem by just fixing the public program directly,” he told me. “But given that we often seem unwilling to do that, this does point to one very real advantage of involvement from private plans.”

3) Many Medicare beneficiaries don’t fill important prescriptions

Rachel Sachs, who studies prescription drug policy at Washington University in St. Louis, highlighted a study on a similar subject that was published in Health Affairs in April 2022, led by Vanderbilt University’s Stacie Dusetzina. The researchers studied the difference in prescription uptake by Medicare beneficiaries who receive a government subsidy to offset their drug costs versus those who do not.

The latter group, who can sometimes be on the hook for hundreds of dollars for every prescription they fill, was substantially less likely to actually use their medication as it had been prescribed, even for serious diagnoses like cancer. People receiving subsidies were twice as likely to fill their prescriptions. The study found that 30 percent of prescriptions for anti-cancer drugs and 22 of prescriptions for hepatitis-C treatment were never started.

The problem of drug affordability for Medicare patients has been an ongoing concern. Because of how the program is currently structured, beneficiaries who are enrolled in the traditional Medicare program but do not qualify for subsidies have no upper limit on how much they can be asked to spend on pharmaceuticals in a given year.

As part of the Inflation Reduction Act, Congress is instituting such a cap for the first time, using savings from the new drug pricing controls also included in the law, capping out-of-pocket costs at $2,000 starting in 2025. That is the kind of intervention the Health Affairs authors were calling for when they published the paper. Now we’ll see if that policy change has an effect on seniors actually taking their medicine.

4) Black and Hispanic Americans are less likely to receive CPR in public spaces

One of the experts I asked for input is Harvard Medical School’s Michael Barnett, who publishes his own overview of the year’s best research every year on Twitter. He sent me a few studies, most of which I’ll let him share in his own overview, but one study in particular stuck out, looking at which people are more (or less) likely to get assistance when they have a health emergency in a public setting with other people around.

The paper, published in the New England Journal of Medicine in October by a collection of scholars across the country, examined more than 100,000 incidents of cardiac arrest that occurred outside of the hospital from 2013 to 2019. They focused in particular on whether the person experiencing cardiac arrest in public received CPR from a bystander.

The results were profound: Black and Hispanic people were significantly less likely to be given CPR than a white person, 45 percent versus 60 percent. And this pattern held across neighborhoods of different racial and socioeconomic make-ups. Whether the neighborhood was predominantly white, Black, or Hispanic, up and down the income ladder, in integrated neighborhoods, white people were more likely to receive CPR than someone who is Black and Hispanic.

“Racial and ethnic differences in bystander CPR in public locations raise additional concerns about implicit and explicit biases in layperson response to out-of-hospital cardiac arrests,” the authors wrote.

Racism within the medical system is well established. Black and Hispanic Americans tend to have less access to health care. They tend to have worse experiences with doctors. Clinical trials and other research does not prioritize them. Medical treatments tend to be developed and designed with white people in mind.

But this study would suggest that even the more casual forms of racism and internalized bias can have a real health effect for marginalized Americans.

5) Prices go up after private equity acquires a physician’s practice

Private equity’s deeper investment into US health care is one of the most important ongoing stories in the field right now. The stakes can be life or death, as one paper that I covered last year about mortality rates in nursing homes purchased by private equity firms found. (Of note this year, according to Harvard’s Amitabh Chandra, was another paper that documented the wide disparities in outcomes among nursing homes, even those who are located in the same area.)

A report published by scholars from Johns Hopkins, Harvard, and Oregon Science & Health University in September 2022 in JAMA Health Forum, which Emma Sandoe of North Carolina Medicaid and Duke University shared with me, examined what happened to costs and care utilization when private equity firms had purchased outpatient practices specializing in ophthalmology, dermatology, and gastroenterology, some of their favorite targets.

The study detected several effects: The cost of individual services went up and those practices were seeing more new patients and also charging more time for their existing patients. The amount billed by the private equity-acquired offices per service increased by 20 percent compared to the study’s control group. They saw 38 percent more new patients and there was a 9 percent increase in the number of existing patient visits that were billed as lasting longer than 30 minutes.

On the surface, that could look like partially good news, in spite of the price hikes, with more patients being seen and spending more time with their doctor. But some of the other findings call into question the value of those increases in service volume. In dermatology, the increase in outpatient visits did not correspond to an increase in biopsies ordered. In the gastroenterology practices, there were more visits and scopes but no notable increase in polyp removals. And likewise, at the eye clinics, there was more diagnostic imaging but not any effect on actual cataract removals.

The authors ended their paper with this warning. “Private equity ownership of physician practices has added a distinctly private and market-driven influence to the broader trends in corporate consolidation of physicians by health systems and insurers,” they wrote. “This study contributes evidence for potential overutilization and higher spending on care that will be important for policy makers to monitor.”