Program Archives - Healthy News

Fitness & Nutrition Workout Challenge Program With DNA Analysis For Women Launch

Push Release

Printed April 4, 2023

This new challenge plan makes use of biometric facts to make individualized fitness and nourishment regimens for its users. The obstacle normally takes place around the system of three months and entails weekly fitness benchmarks, personalised coaching, dietary steering, and significantly extra.

Far more facts is available at https://keap.page/bay721/spring-supply.html

FitFX Global’s newly introduced Spring Into Exercise Challenge has been developed to enable those who are experience trapped and unable to take company about their health and fitness to do so additional correctly, without the need of overexerting themselves. The challenge provides reasonable, achievable objectives with regular 1-on-1 and team check-ins for included accountability.

The obstacle is currently being promoted to people residing in Bethesda, Potomac, and Rockville Maryland in a generate to build the two an on the internet and in-person neighborhood of health-minded individuals there.

The software commences with a biometric examination, which can decide how a member’s genetic profile might effect their health journey so that their personalised prepare can be tweaked accordingly. The DNA screening checks for prospective difficulties such as food items intolerances, genetic predisposition to disease and injury, hormonal equilibrium, as perfectly as macronutrient profile.

Pursuing this assessment, the specialist group who are at the forefront of this system will make a weekly diet plan dependent on that genetic profile. This approach will comprise particular, simple recipes that are developed to maximize the ingestion of total proteins, amino acids, and micronutrients to assistance the overall body and immune method during the duration of the challenge.

This obstacle also presents customers with weekly fitness strategies showcasing 3 virtual pre-recorded exercises. These workout routines are offered by using the FitFX application, which is optimized especially for this challenge and enables users to monitor their development and receive soon after-action stories pursuing every single weekly exercise routine completion.

Guidance is also out there in the form of are living coaching, group counseling, and particular weekly check out-ins with the crew. Around the system of these sessions, members in the software will be guided carefully towards achievement by a supportive group of like-minded people today, all of whom have the exact same ambitions and aspirations.

Throughout the application, contributors will have accessibility to a panel of professionals in areas these as sickness and injuries prevention, corrective physical exercise, athletics nutrition, and actual physical therapy. They will also be invited to be part of an exclusive Fb group to connect on a own amount with other associates for even more aid.

Extra aspects are out there at https://keap.page/bay721/spring-give.html

FITFX World-wide

8453 Oak Bush Terrace,

United States

COMTEX_428324858/2824/2023-04-04T07:33:47

Strength Training & Nutrition Program Launch

Press Release

Published April 5, 2023

Every participant in the new Experienced By Phil on the web coaching program will acquire a weekly 30-minute phone contact to support boost motivation and guarantee frequent progression.

A lot more info is obtainable at https://trainedbyphil.com

The start of Phil’s digital conditioning applications comes as the latest scientific considering at the rear of well being and physical fitness shifts to account for various overall body types, alternatively of the common a single-size-fits-all technique. This knowledge is at the core of Phil’s exercise packages which are formulated to account for the individual’s entire body kind, life-style, diet regime and physical fitness degree.

Phil Catudal has skilled a great number of Hollywood celebs considering that 2006, offering them the instruments to attain their health and fitness goals. He was an early adopter of virtual teaching, which has definitely taken off due to the fact the pandemic. With his software, clients can accessibility health and fitness ideas and workouts by means of his web-site wherever they are in the earth. Consumers can even obtain in depth nourishment programs tailor-made to their unique wants.

“Somewhere around seventy p.c of men and women are performing exercises the erroneous way,” explains Phil. To attain long lasting health and well being, people should perform with their all-natural-born body variety and do the optimal mix of cardio, toughness coaching, and flexibility workouts, as perfectly as consuming the ideal proportion of macronutrients for their physique.

As a regarded professional in fitness and diet, Phil has aided quite a few of Hollywood’s most well known celebrities obtain physique transformations and his achievements speaks for by itself with glowing assessments from clients about the environment. “Phil’s unparalleled awareness of diet blended with energy training classes presents folks the outcomes they require to look good – feel good,” claims Sarah Shahi from Sex Daily life.

Steve Howey from Real Lies echoed equivalent sentiments: “Thanks to Phil Catudal he was significantly much healthier now than ever in advance of! His methods held him inspired and he had been capable to split his personal data each single time.”

In addition to having lots of content clientele in The usa, Phil Catudal’s know-how goes further than borders as he proceeds to increase more countries these as Norway, Dubai, England, Australia and far more on the record of individuals who reward from his software. He also features life coaching companies which focus on helping consumers establish psychological clarity though pursuing physical excellence.

Phil Catudal is an Atlanta-based celebrity physical fitness trainer, wellbeing coach, community speaker and recognised for getting astounding results through online or in human being. He is at the moment doing the job 1-on-one with consumers centered in the Metro-Atlanta place who search for personalized focus and are pushed to live their finest lifestyle.

Interested events can uncover out far more information about Qualified By Phil’s in-man or woman, team and on-line conditioning packages at https://trainedbyphil.com

Properly trained By Phil
[email protected]
+1-470-610-3221
742 Ponce De Leon Pl NE

United States

COMTEX_428429732/2824/2023-04-05T09:36:20

New Zealand rugby-inspired program tackles obesity

Obesity has been continuously increasing across the globe at an alarming rate. In New Zealand (NZ), around 31{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} of adults are obese, and 35{bf0515afdcaddba073662ceb89fbb62b6b1bf123143c0e06b788e1946e8c353f} are overweight, with the prevalence of overweight men significantly greater than women. Notably, Māori and Pasifika men are more obese than non-Māori and non-Pasifika men. Therefore, there is a need for effective and sustainable means of intervention to address issues related to being overweight and obese among NZ men.

Study: Rugby Fans in Training New Zealand (RUFIT NZ): a randomized controlled trial to assess the effectiveness of a healthy lifestyle program for overweight men delivered through professional rugby clubs. Image Credit: Peopleimages.com – Yuri A / Shutterstock.com

Background

Men are mostly underrepresented in the majority of weight loss programs. Based on the reports of fourteen randomized controlled trials (RCTs) linked to men-only weight loss and maintenance programs, a combined intervention of exercise, dietary, and behavior change techniques was found to be most effective.

Motivated by the positive results of a previously developed Football Fans in Training (FFIT) program in Scotland, a similar program was designed in NZ. This new program was developed to support obese or overweight NZ men through professional rugby clubs.

A pilot RCT of Rugby Fans in Training-NZ (RUFIT-NZ) was conducted using 96 participants. Notably, this study documented a weight loss of around 2.5 kg among the participants after 12 weeks of intervention.

In addition to the weight loss, these participants exhibited a decrease in resting heart rate, waist circumference, and diastolic blood pressure. An overall improvement in fitness level was also observed.

Importantly, all participants who completed the program strongly recommended this program to their friends, thereby indicating the possibility of broader acceptance of RUFIT-NZ. Thus, a large-scale RCT was required to assess its sustained effect.

A recent International Journal of Behavioral Nutrition and Physical Activity study determines the efficacy and cost-effectiveness of RUFIT-NZ on lifestyle change, fitness, weight loss, blood pressure, and health-related quality of life (HRQoL).

About the study

A two-arm, multi-center, and parallel RCT was conducted in NZ between January 21, 2019, and October 22 22, 2020. RUFIT-NZ was delivered to participants by professional rugby franchises in a 12-session program.

This study cohort included overweight men between 30 and 65 years of age. These study participants were initially screened through the Physical Activity Readiness Questionnaire (PAR-Q). Any participants who were already associated with other healthy lifestyle programs were excluded.

Weight changes, the primary outcome, were recorded after 52 weeks of intervention. In addition, secondary outcomes such as changes in waist circumference, cardiorespiratory and musculoskeletal fitness, blood pressure, lifestyle behaviors, and HRQoL were evaluated at 12 and 52 weeks.

A total of 308 participants were recruited and randomly divided into two arms, each comprising 154 men. Notably, the study cohort constituted 150 Māori participants.

A wait-list control approach was adopted for the control group, in which participants randomly assigned to this group were asked to continue with their routine lifestyle for 52 weeks. Following this, they were offered RUFIT-NZ intervention at the end of the 12-month follow-up period.

Each RUFIT-NZ intervention session included workshop-based education where the participants learned about the importance of nutrition, sleep, physical activity, and sedentary behavior for about one hour. The following session included one hour of exercise training for the treatment group. Although this was a group-based session, each participant’s exercise was tailored to their individual needs.

Study findings

RUFIT-NZ interventions had overall sustained changes in weight, physical fitness, waist circumference, self-reported physical activity, alcohol consumption, and HRQoL in the treated group. However, no significant change was observed in blood pressure or sleep post-RUFIT-NZ intervention.

Taken together, 200 participants completed the RUFIT-NZ intervention before the implementation of coronavirus disease 2019 (COVID-19) restrictions. The intervention group reported higher consumption of fruits and vegetables at 12 weeks.

At 52 weeks, this group revealed a weight loss of around 2.77 kg. In addition, waist circumference reduction, high physical activity levels, and HRQoL were reduced at 12 and 52 weeks.

The effectiveness of this intervention was also analyzed based on cost per quality-adjusted life year (QALY). Incremental cost-effective ratios of $259 per kg lost or $40,269 per QALY were obtained. A marginal gain in QALY was attributed to the short testing period.

Conclusions

One of the critical limitations of the present trial was related to the lockdowns and restrictions implemented during the COVID-19 pandemic. Due to these restrictions, the RUFIT-NZ intervention could not be delivered to some participants. However, based on the advice of the trial steering committee, data were analyzed for participants from the first two waves.

Another limitation of this study was the absence of blinded outcome assessments.

Despite these limitations, the overall positive primary and secondary outcomes emphasized the efficacy of this intervention in preventing the possible adverse events of morbidity and mortality due to obesity.

Journal reference:

Maddison, R., Hargreaves, E. A., Jiang, Y., et al. (2023) Rugby Fans in Training New Zealand (RUFIT NZ): a randomized controlled trial to assess the effectiveness of a healthy lifestyle program for overweight men delivered through professional rugby clubs. International Journal of Behavioral Nutrition and Physical Activity 20 (37). doi:10.1186/s12966-022-01395-w, https://ijbnpa.biomedcentral.com/articles/10.1186/s12966-022-01395-w

Bay Pines VA Research Program | VA Bay Pines Health Care

Study Area Psoriasis Title/BP Study Number A Multicenter, Open Registry of Patients with Psoriasis who are Candidates for Systemic Therapy Including Biologics “PSOLAR” Study #1573980 Synopsis Observational Study collecting information related to the treatment of psoriasis and evaluates patient and disease characteristics, patient-reported assessments and clinical and quality of life outcomes. Clinical Trials: NCT00508547 Study Team Local PI: Daniel Hogan, MD Lori Sisler lorine.sisler@va.gov 727-385-0223 Sarah Crim sarah.crim@va.gov 727-398-6661, ext. 17975 Status Enrolling Study Area Genetics Title/BP Study Number Million Veteran Program “MVP” Study #1612959 Synopsis A national research program to learn how genes, lifestyle, and military exposures affect health and illness. All Veterans can participate in this one-time blood collection project. Study Team Local PI: Allison Williams, RN, Ph.D., ND Gary Smith gary.smith@va.gov 727-398-6661, ext.17284 Lori Sisler lorine.sisler@va.gov 727-385-0223 Status Enrolling Study Area Opioid Abuse Title/BP Study Number Comparative Effectiveness of Two Formulations of Buprenorphine for Treating Opioid Use Disorder in Veterans “VA BRAVE” CSP 2014 Study #1612560 Synopsis Treat Veterans with Opioid Use Disorder (OUD) to understand whether Buprenorphine a medication to treat OUD, given in a monthly injection form works similarly to or better than buprenorphine oral form. Participation in the study will last 1 year. Clinical Trials: NCT04375033 Study Team Local PI: Maha Lahoud-Bladykas, MD Chris Vallanat christopher.vallanat@va.gov 727-398-6661, ext. 15992 Mariah Alexis mariah.alexis@va.gov 727-398-6661, ext. 10152 Status Enrolling Study Area Opioid Abuse Title/BP Study Number A Randomized, Double-Blind Study Comparing 2 Maintenance Dosing Regimens of Buprenorphine Extended-Release Subcutaneous Injection (RBP-6000) in Treatment-Seeking Adult Participants with Opioid Use Disorder and High-risk Opioid Use ”INDIVIOR” Study #1651131 Synopsis The primary objective of the maintenance phase is to compare the efficacy of 100 mg and 300 mg maintenance doses of extended-release buprenorphine administered every 4 weeks. Clinical Trials: NCT04995029 Study Team Local PI: Maha Lahoud-Bladykas, MD Mariah Alexis mariah.alexis@va.gov 727-398-6661, ext. 10152 Chayla Lee Chayla.lee@va.gov 727-398-6661, ext. 10111 Status To be launched Study Area Lung Cancer Title/BP Study Number Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy Trial “VALOR” CSP 2005 Study #1573963 Synopsis Veterans diagnosed with stage I non-small cell lung cancer who are healthy enough to have surgery, agree to be randomized to either surgery (standard of care treatment) or an alternative non-surgical treatment – Stereotactic Radiotherapy (SBRT). Clinical Trials: NCT02984761 Study Team Local PIs: Edward Hong, MD Ryan Burri, MD Marlena Kern, RN marlene.kern@va.gov (VA cell) 727-219-7174 Status Enrolling Study Area PTSD/Mental Health Title/BP Study Number Veteran Health Behavior Study (Wave 2) Study #1573969 Synopsis Observational trial recruiting Veterans who were deployed to Iraq or Afghanistan to learn more about the bidirectional relationships between sleep quality, PTSD symptoms and Alcohol Use Disorder symptoms. Clinical Trials: NCT04552782 Study Team Local PI: Jessica Keith, PhD Anna Rosenblatt Anna.Rosenblatt2@va.gov 727-398-6661, ext.14728 or 727-317-7361 Camille Compton Lori.Compton@va.gov 727-398-6661, ext. 14728 or 10151 Status Enrolling Study Area Infectious Disease Title/BP Study Number Randomized, Double-blind, Placebo-controlled, Multicenter Phase 3 Study to Assess the Efficacy, Safety And Immunogenicity of Vaccination With ExPEC9V Study #1624732 Synopsis Phase III clinical trial to evaluate the safety and efficacy of Vaccination With ExPEC9V in the Prevention of Invasive Extraintestinal Pathogenic Escherichia coli Disease in Adults Aged 60 Years And Older with a History of Urinary Tract Infection in the Past 2 Years. Clinical Trials: NCT04899336 Study Team Local PI: Kaley Tash, MD Anna Rosenblatt Anna.Rosenblatt2@va.gov 727-398-6661, ext.17051 or 727-317-7361 Cortny Withee Cortny.Withee@va.gov 727-398-6661, ext.15900 Status Enrolling Study Area PTSD/Insomnia Title/BP Study Number CSP #2016 National Adaptive Trial for PTSD related Insomnia (NAP) Study #1612520 Synopsis A clinical trial to compare the efficacy of trazodone hydrochloride, eszopiclone, and gabapentin to placebo, as adjunctive therapies in the treatment of insomnia symptoms among Veterans with military related PTSD. Study Team Local PI: Ateiat Philips, MD Stella Inting-Toothman 727-398-6661, ext. 17184 727-776-8687 Stella.inting-toothman@va.gov Status Enrolling Study Area Psoriatic Arthritis Title/BP Study Number Solstice- Guselkumab therapy in patients with active Psoraitic Arthritis (PsA) Study #1634796 Synopsis For Veterans with active psoriatic arthritis who have failed a prior anti-TNF (Humira, Enbrel, etc.) The primary objective is to evaluate the efficacy of guselkumab. Study Team Local PI: Priyanka Murali, MD Sarah Crim sarah.crim@va.gov 727-398-6661, ext. 17975 Camille Compton Camille.compton@va.gov 727-398-6661, ext. 14728 or 10151 Status Enrolling Study Area Psoriatic Arthritis Title/BP Study Number Star- Guselkumab therapy in patients with Psoraitic Arthritis (PsA) who have never been treated with a biologic before Study #1634798 Synopsis For bionaive Veterans who have never been treated with a biologic participants with psoriatic arthritis axial disease. The goal is to evaluate the efficacy of guselkumab by assessing reduction in axial symptoms. Study Team Local PI: Priyanka Murali, MD Sarah Crim sarah.crim@va.gov 727-398-6661, ext. 17975 Camille Compton Camille.compton@va.gov 727-398-6661, ext. 14728 or 10151 Status Enrolling Study Area Psoriatic Arthritis Title/BP Study Number Affinity- Combination therapy with guselkumab and golimumab in patients with Psoriatic Arthritis (PsA) Study #1634801 Synopsis For Veterans with active psoriatic arthritis, who have failed prior treatment of anti-TNF (Humira, Enbrel, etc.) and are interested in a dual therapy of guselkumab AND golimumab. Study Team Local PI: Priyanka Murali, MD Sarah Crim sarah.crim@va.gov 727-398-6661, ext. 17975 Camille Compton Camille.compton@va.gov 727-398-6661, ext. 14728 or 10151 Status Enrolling Study Area Cardiology Title/BP Study Number Pragmatic Evaluation of Events and Benefits of Lipid-Lowering in Older Adults (PREVENTABLE) Trial Study #1612747 Synopsis PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study that will evaluate if taking a statin could help older adults live independently for longer by preventing dementia, disability, or heart disease. PREVENTABLE will randomly assign Atorvastatin 40 mg daily or matching placebo once daily to 20,000 community-dwelling adults ≥75 years of age without clinically evident cardiovascular disease, significant disability, or dementia, and follow them for up to 5 years. Clinical Trials: NCT04262206 Study Team Local PI: Dennis Hall Chayla Lee Chayla.lee@va.gov 727-398-6661, ext. 10111 Cortny Withee Cortny.Withee@va.gov 727-398-6661, ext. 15900 Status Enrolling Study Area Infectious Disease Title/BP Study Number CSP #2001 Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics (VA INTREPID) Study #1613455 Synopsis VA Cooperative Study #2001 is a prospective, randomized, double-blind investigation of the addition of 6 weeks of rifampin, 600 mg daily, vs. matched placebo (riboflavin) to standard-of-care, backbone antimicrobial therapy for Diabetic Foot Osteomyelitis. The primary endpoint is amputation-free survival. Clinical Trials: NCT03012529 Study Team Local PI: Melissa Abercrombie, MD Cortny Withee Cortny.Withee@va.gov 727-398-6661, ext. 15900 Sarah Crim sarah.crim@va.gov 727-398-6661, ext. 17975 Status Enrolling Study Area Infectious Disease Title/BP Study Number CSP #596 Optimal Treatment for Recurrent Clostridium difficile Infection (OpTION) Study #1613094 Synopsis The primary objective of this study is to determine whether 1) standard fidaxomicin treatment and 2) standard vancomycin treatment followed by taper and pulse vancomycin treatment are superior to standard vancomycin treatment alone for sustained clinical response at day 59 for all treatments, for participants with either their first or second recurrence of C. difficile infection. Clinical Trials: NCT02667418 Study Team Local PI: Kaley Tash, MD Cortny Withee Cortny.Withee@va.gov 727-398-6661, ext. 15900 Sarah Crim sarah.crim@va.gov 727-398-6661, ext. 17975 Status Enrolling Study Area Cardiology Title/BP Study Number CSP2002 VA-IMPACT Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes Study #TBD Synopsis VA Cooperative Studies Program #2002 will determine whether treatment with metformin, compared with placebo, reduces the risk of major adverse cardiovascular events (MACE) in patients with pre-diabetes and established atherosclerotic cardiovascular disease (ASCVD). Study Team Local PI: Manjunath Harlapur, MD Stella Inting-Toothman (727) 398-6661, ext. 17184 (727) 776-8687 Stella.inting-toothman@va.gov Sarah Crim sarah.crim@va.gov 727-398-6661, ext. 17975 Status To be launched Study Area Lung Cancer Title/BP Study Number LungLife AI Inc. Study #1651410 Synopsis The objective of this study is to use blood draws to validate a device developed by LungLife AI Inc in detecting circulating tumor cells for patients presenting with pulmonary nodules. The test aims to aid in the detection of early-stage lung cancer. Clinical Trials: NCT05171491 Study Team Local PI: Stephen Clum, MD Camille Compton Lori.compton@va.gov 727-398-6661, ext. 10151 Mariah Alexis Mariah.alexis@va.gov 727-398-6661, ext. 10152 Kameron Wheelock Kameron.wheelock@va.gov 727-398-6661, ext. 17842 Status Enrolling Study Area Prostate Cancer Title/BP Study Number Identification of Targetable Prostate Cancer Alterations Through Tumor DNA Screening Study #1573965 Synopsis This is an observational, non-interventional study of screening veterans receiving care within Bay Pines VA Healthcare System who carry the diagnosis of advanced prostate cancer, metastatic or recurrent, for the presence of DNA mutations in tumor or germline DNA which could provide access to therapies with potential to significantly prolong survival. Study Team Local PI: Ryan Burri, MD Hayley Maither Hayley.maither@va.gov 727-398-6661, ext. 15925 Kameron Wheelock Kameron.Wheelock@va.gov 727-398-6661, ext. 17842 Mariah Alexis Mariah.Alexis@va.gov 727-398-6661, ext. 10152 Status Enrolling Study Area Prostate Cancer Title/BP Study Number VA STARPORT: Veterans Affairs Seamless Phase II/III Randomized Trial of Standard Systemic Therapy with or without PET-directed Local Therapy for Oligorecurrent Prostate Cancer Study #1616760 Synopsis This is an interventional study for patients with oligorecurrent prostate cancer to determine whether adding metastasis-directed therapy to standard systemic therapy improves disease outcomes further. This study also determines if certain mutations present in tumor DNA can predict if Veterans will benefit from PET-directed local therapy. Study Team Local PI: Ryan Burri, MD Hayley Maither Hayley.maither@va.gov 727-398-6661, ext. 15925 Kameron Wheelock Kameron.Wheelock@va.gov 727-398-6661, ext. 17842 Status Enrolling Study Area Lung Cancer Title/BP Study Number A Phase III, Randomized, Placebo-controlled, Double-blind, Multi-center, International Study of Durvalumab with Stereotactic Body Radiation Therapy (SBRT) for the Treatment of Patients with unresected Stage I/II, lymph-node negative Non-small Cell Lung Cancer (PACIFIC-4/RTOG-3515) Study #1600510 Synopsis This is a study assessing the efficacy and safety of durvalumab versus placebo with standard of care Stereotactic Body Radiation Therapy (SBRT) in patients with unresected clinical Stage I/II lymph node-negative (T1 to T3N0M0) Non-Small Cell Lung Cancer. Study Team Local PI: Ryan Burri, MD Kameron Wheelock Kameron.Wheelock@va.gov 727-398-6661, ext. 17842 Hayley Maither Hayley.maither@va.gov 727-398-6661, ext. 15925 Status Enrolling Study Area Bladder Cancer Title/BP Study Number A Phase 3, Randomized, Double-blind, Placebo-controlled Clinical Trial to Study the Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) versus CRT Alone in Participants with Muscle-invasive Bladder Cancer (MIBC). Study #1573968 Synopsis This is a trial for muscle-invasive bladder cancer to compare intact event-free survival in participants from Arm A (pembrolizumab + chemoradiotherapy) and Arm B (placebo + chemoradiotherapy). Study Team Local PI: Andrew Leone, MD Hayley Maither Hayley.maither@va.gov 727-398-6661, ext. 15925 Kameron Wheelock Kameron.Wheelock@va.gov 727-398-6661, ext. 17842 Status Enrolling Study Area Lung Cancer Title/BP Study Number A Phase 2 Trial of MRTX849 Monotherapy and in Combination with Pembrolizumab in Patients with Advanced Non-Small Cell Lung Cancer with KRAS G12C Mutation Study #1679339 Synopsis This is a study assessing the efficacy and safety of MRTX849 alone and in combination with Pembrolizumab as a first-line treatment in patients with Advanced Non-Small Cell Lung Cancer with a KRAS G12C mutation. Patients will be randomized to different arms depending on their Tumor Progression Score (TPS). Study Team Local PI: Ryan Burri, MD Kameron Wheelock Kameron.Wheelock@va.gov 727-398-6661, ext. 17842 Hayley Maither Hayley.maither@va.gov 727-398-6661, ext. 15925 Mariah Alexis Mariah.Alexis@va.gov 727-398-6661, ext. 10152 Status Enrolling Study Area Bladder Cancer Title/BP Study Number An observational study of efficacy and utility of Cxbladder tests in the identification of low vs high risk patients and the detection of urothelial carcinoma in patients presenting with hematuria Study #1683093 Synopsis This is an observational study recruiting patients presenting with blood in the urine, who are undergoing investigation for the presence of Urothelial Carcinoma. This study is designed to compare the Cxbladder tests versus standard of care procedures. Study Team Local PI: Andrew Leone, MD Mariah Alexis Mariah.Alexis@va.gov 727-398-6661, ext. 10152 Hayley Maither Hayley.maither@va.gov 727-398-6661, ext. 15925 Kameron Wheelock Kameron.Wheelock@va.gov 727-398-6661, ext. 17842 Status To be launched Study Area Head and Neck Cancer Title/BP Study Number Randomized Phase II/III Trial of Radiation with High-Dose Cisplatin (100 mg/m2) Every Three Weeks versus Radiation with Low-Dose Weekly Cisplatin (40 mg/m2) for Patients with Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN) Clinical Trials: NCT05050162. Study #1682403 Synopsis This study for patients with locoregionally advanced squamous cell carcinoma of the head and neck is to determine whether radiation with low-dose cisplatin weekly is superior in terms of acute toxicity to radiation with high-dose cisplatin every 3 weeks. Study Team Local PI: Ryan Burri, MD Hayley Maither Hayley.maither@va.gov 727-398-6661, ext. 15925 Kameron Wheelock Kameron.Wheelock@va.gov 727-398-6661, ext. 17842 Mariah Alexis Mariah.Alexis@va.gov 727-398-6661, ext. 10152 Status Enrolling Study Area Prostate Cancer Title/BP Study Number A Single-arm, Open-label, Phase II Study of Checkpoint Inhibitors in Men with Progressive Metastatic Castrate Prostate Cancer (mCRPC) Characterized by a Mismatch Repair Deficiency or Biallelic CDK12 Inactivation (CHOMP). Study #1612473 Synopsis The purpose of this study is to determine the response rate to the anti-PD1 antibody, pembrolizumab in Veterans with mCRPC characterized by either mismatch repair deficiency (dMMR) or biallelic inactivation of CDK12. Study Team Local PI: Ryan Burri, MD Hayley Maither Hayley.maither@va.gov 727-398-6661, ext. 15925 Kameron Wheelock Kameron.Wheelock@va.gov 727-398-6661, ext. 17842 Status Enrolling Study Area Prostate Cancer Title/BP Study Number An open-label, multicenter phase II study to compare the efficacy of carboplatin as first-line followed by second-line olaparib versus olaparib as first-line followed by second-line carboplatin in the treatment of patients with castration resistant prostate cancer containing homologous recombination deficiency (COBRA). Study #1612483 Synopsis To determine progression free survival (PFS) to initial therapy (PFS-1L) with carboplatin vs. olaparib in the treatment of patients with metastatic castration resistant prostate cancer (mCRPC) containing inactivation of the homologous DNA repair pathway, including BRCA1, BRCA2, PALB2, BARD1, BRIP1, CHEK1, FANCL, RAD51B, RAD51C, and RAD54L. Study Team Local PI: Ryan Burri, MD Kameron Wheelock Kameron.Wheelock@va.gov 727-398-6661, ext. 17842 Hayley Maither Hayley.maither@va.gov 727-398-6661, ext. 15925 Status Enrolling Study Area Prostate Cancer Title/BP Study Number VA Multi-Omics Analysis Platform for Prostate Cancer and Sequencing (VA MAPP-SEQ) Biorepository Study #1713735 Synopsis Biorepository for men with the potential to be diagnosed with prostate cancer or having a diagnosis of prostate cancer scheduled to undergo surgical/non-surgical procedure on the prostate gland or metastatic tissue. The purpose of this study is to create a centralized biorepository for future research for Veterans with prostate cancer. Study Team Local PI: Andrew Leone, MD Hayley Maither Hayley.maither@va.gov 727-398-6661, ext. 15925 Kameron Wheelock Kameron.Wheelock@va.gov 727-398-6661, ext. 17842 Mariah Alexis Mariah.Alexis@va.gov 727-398-6661, ext. 10152 Status Enrolling Study Area Pulmonary/COPD Title/BP Study Number A Phase III, Multicenter, Randomized, Double-blind, Chronic-dosing, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy and Safety to Two Dose Regimens of MEDI3506 in Participants with Symptomatic Chronic Obstructive Pulmonary Disease (COPD) with a History of COPD Exacerbations (TITANIA). Study #1672631 Synopsis For Veterans 40 years and older with a diagnosis of COPD who have a history of exacerbations within the past year. The goal is to evaluate the efficacy and safety of MEDI3506 300 mg every 8 weeks and 300 mg every 4 weeks dose regimens. The study is to be conducted. Study Team Local PI: Ravi Patel, MD Sarah Crim Sarah.Crim@va.gov 727-398-6661, ext. 17975 Lori Camille Compton Lori.Compton@va.gov 727-398-6661, ext. 10151 Chayla Lee Chayla.Lee@va.gov 727-398-6661, ext. 10111 Status Enrolling Study Area Cardiology Title/BP Study Number A Multi-Center Study Evaluating Participants who Received CanGaroo® Envelope, TYRX™ Envelope, or No Envelope During CIED Implantation. Study #1605396 Synopsis The purpose of this study is to look at the differences of healing and complications in patients who have had previous heart device procedures done. The study will compare the results of the previous procedure (a type of envelope used or no envelope used). Clinical Trials: NCT04645173 Study Team Local PI: Afolabi Sangosanya, MD Cortny Withee Cortny.Withee@va.gov 727-398-6661, ext. 15900 Lori Camille Compton Lori.Compton@va.gov 727-398-6661, ext. 10151 Chayla Lee Chayla.Lee@va.gov 727-398-6661, ext. 10111 Status Enrolling

Aging Strong: Fitness and nutrition program coming to Warrior House | Lifestyles

OAKFIELD – A Health Equity Award form Univera Healthcare will allow Warrior House of WNY to bring an Aging Strong Program to its community center at 33 South Main St.

Univera equity award bolsters Warrior House ‘Aging Strong Program’

Any person up for a little downward pet?

In their ongoing quest to give packages for the community’s very well-remaining, organizers of The GOOSE Neighborhood Center and Warrior Home of WNY will now be featuring a yoga sequence, thanks to a Univera overall health fairness award, Susan Zeliff states.

The award from Univera Healthcare will support Warrior Home of WNY and its Aging Solid Application to encourage physical wellness between senior older people aged 55 and older in rural Genesee County. Based in Oakfield, Warrior Household is a nonprofit organization committed to enriching the lives of veterans and households through Western New York by means of support providers that endorse social and emotional improvement for all round health and fitness and well-becoming, said Zeliff, Warrior Dwelling co-founder and treasurer.

“Aging Powerful is a community-based mostly health and diet plan that informs and empowers more mature older people to make balanced choices about taking in, and safely raise their amount of physical activity,” Zeliff explained this weekend. “In our section of Genesee County, the want for this kind of software is good, but existing resources were couple of. That is right until Univera stepped in with underwriting aid.”

Warrior Dwelling of WNY is located at 33 South Key St., in The GOOSE Community Heart, a identify borrowed from the former internet site of the Yellow Goose and an acronym for the Warrior House motto: God is On Our Side Every day.

Univera Health care is a nonprofit well being program that serves associates across the eight counties of Western New York and invited nonprofit, 501(c)(3) businesses serving Western New York to utilize for Health Equity Awards to enable fund health and wellness packages that address racial and ethnic health disparities.

Health and fitness Fairness categories integrated but were not confined to: Lessening wellbeing disparities in racial, ethnic, LGBTQ communities, people with disabilities, people living in rural or city communities, or other teams that might be at higher well being possibility for clinical difficulties and problems (long-term or acute), behavioral wellness or mental wellness disorders, and negative outcomes from the previously mentioned, together with death or suicide.

“Working jointly with businesses such as Warrior House, we are confronting the disaster in health disparities, and addressing prolonged-standing gaps in treatment and products and services in underserved communities,” Univera Healthcare President Artwork Wingerter mentioned.

Univera Health care invited companies to implement for awards of up to $30,000 every single to support fund packages to enhance health and fitness fairness in communities of color, specially inside Black and Latino communities. These segments of the group go on to endure from health treatment and social cons thanks to racism and discrimination. Award categories consist of, but have been not constrained to, strengthening the community’s actual physical wellness and mental health and fitness, cutting down social disparities in health care, and guaranteeing access to health and fitness treatment expert services.

The funding from Univera Health care will guidance six nonprofit, 501(c)(3) corporations across Western New York, that had been chosen soon after a comprehensive review approach that integrated enter from people today with various backgrounds and ordeals to evaluate each individual proposal. Grant recipients have been picked primarily based on obvious, outlined targets and measurable success for reducing wellness disparities and strengthening overall health fairness.

Univera Health care introduced the award to Warrior Dwelling on Feb. 2. The target of the Getting old Solid method is to market actual physical well being amid senior adults 55 and more mature by means of a neighborhood-based exercise and diet plan that informs and empowers more mature adults to make nutritious possibilities about feeding on and safely and securely increasing their physical activity amounts, Zeliff stated.

Secondary aims include cultivating supportive networks amid older-aged community customers, selling health and fitness training and literacy through health and diet workshops, and awareness of accessible help from community health support vendors and the Warrior Dwelling food stuff pantry.

Funds will be used for plan analysis, materials, foodstuff, and for exercising instructor Denise Gliden. She will be hosting a chair yoga at 10 a.m. on Thursday mornings beginning March 16 and a Vinyasa-model yoga at 6 p.m. on Wednesday nights beginning March 22.

“Our Univera Award will allow us to give these lessons for totally free. Our target is often to offer low to no-expense plans. We by no means want expenditures to hold people today from collaborating in our programs,” Zeliff stated. “It is awards like this that aid us make this achievable. At this time, we are not putting a limit on the class sizing. We are hoping to reward a lot of men and women with this software.”

For far more data, go to Warrior Household of WNY or Univera Healthcare.

Submitted image of Michele Hrichan, Univera Health care Medicare Income Olivia Linke, Univera Health care Neighborhood Affairs Director Susan Zeliff, Warrior Home of WNY co-founder and Treasurer Art Wingerter, Univera Healthcare president and Kimberly Burr, Univera Healthcare Marketplace Enroller.